A. Wrong, Cells were lacking the peculiar cross-striations of rhabdomyoma and the spider-web appearance.
B. Wrong, The lesion was not capsulated and cells lack the characteristic appearance of oncocytes (centrally placed nuclei with prominent nucleoli.
C. Right, The lesion was formed of sheets of eosinophilic granular cells with syncytial appearance. The cells were infiltrating the underlying muscles and many of them showed Pustulo-ovoid bodies of Milian (circles). Multiple Granular Cell Tumor could be seen in association with LEOPARD, Noonan and NF1 syndromes.
C. Right, The lesion was formed of sheets of eosinophilic granular cells with syncytial appearance. The cells were infiltrating the underlying muscles and many of them showed Pustulo-ovoid bodies of Milian (circles). Multiple Granular Cell Tumor could be seen in association with LEOPARD, Noonan and NF1 syndromes.
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