A. Right, the lesion appeared radiographically as ill-defined mixed lesion with pathological fracture. Histologically it was formed of chronically inflamed granulation tissue with new bone formation and sequestra. The patient reported that he is an addictive to Crystal meth (methamphetamine), which is reported to cause osteonecrosis of the jaws (Methamphetamine-induced osteonecrosis).
As a further side effect of methamphetamine abuse, a condition known as “meth mouth” has been increasingly reported and is characterized by xerostomia, extensive carious lesions, enamel erosions, extensive teeth crunching, bruxism, muscle trismus, and lockjaw.
B. Wrong, there was no atypia in the chronically inflamed granulation tissue; which exclude the probability of malignancy.
C. Wrong, the formed granulation tissue was bland with evidence of new bone formation at the periphery, which excluding malignancy. As well as, the presence of sequestra with empty bone lacunae confirm the diagnosis of osteonecrosis.
A. Right, the lesion appeared radiographically as ill-defined mixed lesion with pathological fracture. Histologically it was formed of chronically inflamed granulation tissue with new bone formation and sequestra. The patient reported that he is an addictive to Crystal meth (methamphetamine), which is reported to cause osteonecrosis of the jaws (Methamphetamine-induced osteonecrosis).
As a further side effect of methamphetamine abuse, a condition known as “meth mouth” has been increasingly reported and is characterized by xerostomia, extensive carious lesions, enamel erosions, extensive teeth crunching, bruxism, muscle trismus, and lockjaw.
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