A. Right, All microscopic fields showed lipoblasts and lipocytes dispersed within spindle cell proliferation. S100 and vimentin were patchy positive, while Sox10 was negative indicating that the lesion was neural crest derived but not neural nor melanotic origin. Moreover, MDM2 was focally positive favoring the diagnosis of well-differentiated spindle cell liposarcoma.
B. Wrong, PanCK and calponin were negative in the spindle cell proliferation excluding myoepithelial origin.
C. Wrong, PanCK and calponin were negative in the spindle cell proliferation excluding myoepithelial origin.
Right, All microscopic fields showed lipoblasts and lipocytes dispersed within spindle cell proliferation. S100 and vimentin were patchy positive, while Sox10 was negative indicating that the lesion was neural crest derived but not neural nor melanotic origin. Moreover, MDM2 was focally positive favoring the diagnosis of well-differentiated spindle cell liposarcoma.